922+ Matlacha Isles Holiday Rentals & Private Villas

Find Family-Friendly Holiday Rentals in or near Matlacha Isles

Discover more than 922 treehouse rentals in Matlacha Isles, perfect for your holiday adventure. Treehouse offers treetop accommodations with everything you need for a relaxing escape near Matlacha Isles, FL.

Whether you're seeking luxury multi-level treehouses, rustic forest cabins, cozy off-grid retreats, or family-friendly treehouse lodgings, we can help you find the ideal place. Our rentals feature top-notch amenities such as private decks, fully equipped kitchens, fire pits, hot tubs, and Wi-Fi, ensuring your group enjoys a comfortable and memorable stay.

Planning a group getaway to Matlacha Isles? TreeHouse guarantees a unique and unforgettable experience with plenty of options for families, large groups, or private rentals for long or short stays. Explore our Matlacha Isles pet-friendly treehouse rentals and easily book your dream treehouse vacation rental in Matlacha Isles with TreeHouse.

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Frequently Asked Questions About Matlacha Isles Holiday Rentals

There are a lot of options in Matlacha Isles. If you plan on staying in the Matlacha Isles area, consider making a reservation for a few nights at one of these properties as these have been rated the top Holiday Home Rentals in Matlacha Isles:

There are many holiday rentals available in Matlacha Isles; however, here are a few of the most popular holiday homes listed in Matlacha Isles on our website:
At Treehouse Rentals most of our places to stay are perfect for families. Check out the complete list of holiday homes in Matlacha Isles to find one that works for you.
Yes, there are 922 self-catering family homes and holiday rentals in Matlacha Isles.
There are more than 922 luxury holiday homes in or near Matlacha Isles, according to 2025 data from Treehouse Rentals. Consider these homes for your next holiday:
Yes, there are 922 pet friendly rentals that are available in Matlacha Isles.